Boronic Acid and Trifluoroborate Prices for Suzuki Coupling: US vs China (October 2026)

This report compares what seven boron reagents used in Suzuki–Miyaura cross-coupling cost in the United States and in China: three boronic acids (phenylboronic acid, 4-fluorophenylboronic acid and methylboronic acid), a boronic acid pinacol ester (trans-2-ethoxyvinylboronic acid pinacol ester), two potassium organotrifluoroborates (potassium vinyltrifluoroborate and potassium N-Boc-aminomethyltrifluoroborate) and diboron tetrahydroxide, a borylation reagent.

Boron reagents are dosed in molar equivalents, and the molecular weights of these seven range from 60 to 237. So besides the price per pack, this report gives the price per gram and the price per mole.

All figures come from the GrapeCat Chem regional price index. They are list prices observed between 13 and 16 October 2026, converted to US dollars at the European Central Bank reference rate. Every comparison uses the same stated purity and the same pack size in both regions. The values are research benchmarks, not quotations or offers.

Key findings

• At the 100 g pack, the US list price was 1.5 to 6.7 times the China index: phenylboronic acid 6.72×, 4-fluorophenylboronic acid 3.88×, potassium N-Boc-aminomethyltrifluoroborate 3.44×, methylboronic acid 3.02×, potassium vinyltrifluoroborate 2.90×, diboron tetrahydroxide 2.04× and trans-2-ethoxyvinylboronic acid pinacol ester 1.53×.
• Phenylboronic acid was the cheapest of the seven in China: $17.78 for 100 g (9 sources) and $160.02 for 1 kg (4 sources), or $0.16 per gram.
• Per mole, methylboronic acid and phenylboronic acid cost about the same in China at the 100 g pack, $24 and $22, although methylboronic acid cost 2.2 times as much per gram. Its molecular weight is less than half that of phenylboronic acid.
• The two potassium trifluoroborates cost more per mole than the three boronic acids: $105 for the vinyl salt and $1,499 for the N-Boc-aminomethyl salt, against $22 to $43 for the boronic acids (China index, 100 g pack).
• The US list prices of phenylboronic acid and 4-fluorophenylboronic acid were identical at every pack from 5 g to 1 kg, while in China 4-fluorophenylboronic acid cost 1.7 times as much at 100 g.
• Larger packs were usually much cheaper per gram in China: potassium vinyltrifluoroborate fell 79% from 1 g to 100 g, and phenylboronic acid 78% from 5 g to 1 kg. There were exceptions: methylboronic acid cost slightly more per gram at 500 g than at 100 g, and the ethoxyvinyl pinacol ester more at 100 g than at 25 g.

Price comparison at the 100 g pack

• Phenylboronic acid (CAS 98-80-6), 98%: US $119.53; China $17.78 (9 sources). US is 6.72× China. Per mole: US $146, China $22.
• 4-Fluorophenylboronic acid (CAS 1765-93-1), 98%: US $119.53; China $30.78 (6 sources). US is 3.88× China. Per mole: US $167, China $43.
• Potassium N-Boc-aminomethyltrifluoroborate (CAS 1314538-55-0), 95%: US $2,175.99; China $632.10 (4 sources). US is 3.44× China. Per mole: US $5,159, China $1,499.
• Methylboronic acid (CAS 13061-96-6), 98%: US $119.56; China $39.53 (10 sources). US is 3.02× China. Per mole: US $72, China $24.
• Potassium vinyltrifluoroborate (CAS 13682-77-4), 97%: US $227.16; China $78.46 (5 sources). US is 2.90× China. Per mole: US $304, China $105.
• Diboron tetrahydroxide (CAS 13675-18-8), 95%: US $100.43; China $49.30 (1 source). US is 2.04× China. Per mole: US $90, China $44.
• trans-2-Ethoxyvinylboronic acid pinacol ester (CAS 1201905-61-4), 98%: US $430.33; China $280.54 (4 sources). US is 1.53× China. Per mole: US $852, China $556.

Phenylboronic acid

Phenylboronic acid (C6H7BO2, molecular weight 121.93) is the simplest arylboronic acid. At 98% purity the China index was $3.67 for 5 g (4 sources), $4.63 for 25 g (9 sources), $17.78 for 100 g (9 sources), $83.37 for 500 g (7 sources) and $160.02 for 1 kg (4 sources). The US list prices were $23.91, $47.81, $119.53, $358.58 and $597.64, 3.7 to 10.3 times the China index.

In China, 25 g cost only 26% more than 5 g, so the price per gram fell from $0.73 at 5 g to $0.19 at 25 g, and then more slowly to $0.16 at 1 kg.

4-Fluorophenylboronic acid

4-Fluorophenylboronic acid (C6H6BFO2, molecular weight 139.92) at 98% purity: China $4.48 for 5 g (7 sources), $9.03 for 25 g (8 sources), $30.78 for 100 g (6 sources), $141.34 for 500 g (5 sources) and $195.28 for 1 kg (1 source). The US list prices were the same as for phenylboronic acid at every pack, $23.91 to $597.64, which made them 2.5 to 5.3 times the China index.

In China it cost 1.7 times as much as phenylboronic acid at 100 g, and about twice as much per mole ($43 against $22). The price per gram fell 68% from 5 g ($0.90) to 500 g ($0.28).

Methylboronic acid

Methylboronic acid (CH5BO2, molecular weight 59.86) at 98% purity: China $4.11 for 5 g (8 sources), $10.84 for 25 g (10 sources), $39.53 for 100 g (10 sources), $206.24 for 500 g (6 sources) and $365.11 for 1 kg (4 sources). The US list prices were $23.91, $47.82, $119.56, $430.42 and $836.92, 2.1 to 5.8 times the China index.

Per gram, methylboronic acid cost 2.2 times as much as phenylboronic acid in China at 100 g ($0.40 against $0.18). Per mole the two were close: $24 against $22. Its China price per gram changed little beyond 100 g: $0.40 at 100 g, $0.41 at 500 g and $0.37 at 1 kg.

Potassium vinyltrifluoroborate

Potassium vinyltrifluoroborate (C2H3BF3K, molecular weight 133.95) is priced at two purities. At 97% the China index was $3.81 for 1 g (6 sources), $5.83 for 5 g (7 sources), $21.67 for 25 g (7 sources), $78.46 for 100 g (5 sources) and $283.06 for 500 g (1 source). The US list prices were $23.91, $35.87, $71.74, $227.16 and $1,076.04, 2.9 to 6.3 times the China index.

At 95% the China index was $4.40 for 1 g (4 sources), $5.23 for 5 g (7 sources) and $7.17 for 10 g (4 sources). The US listing at this purity was $54.85, $58.43 and $60.38, 8.4 to 12.5 times the China index and higher than the US listing at 97%.

At 97% the China price per gram fell 79%, from $3.81 at 1 g to $0.78 at 100 g.

Potassium N-Boc-aminomethyltrifluoroborate

Potassium N-Boc-aminomethyltrifluoroborate (C6H12BF3KNO2, molecular weight 237.07) was the most expensive reagent in this report. At 95% purity the China index was $15.99 for 1 g (7 sources), $61.13 for 5 g (7 sources), $99.83 for 10 g (3 sources), $189.21 for 25 g (4 sources) and $632.10 for 100 g (4 sources). The US list prices were $45.36, $167.91 and $282.69 for 1 g, 5 g and 10 g (2 sources each), $657.58 for 25 g and $2,175.99 for 100 g.

It is the only reagent here with two US sources at some packs, and its US-to-China ratio was the most stable of the seven, between 2.75× and 3.48×. Per mole at 100 g it cost $1,499 in the China index and $5,159 in the US list price.

Diboron tetrahydroxide

Diboron tetrahydroxide (B2H4O4, molecular weight 89.66), also listed as tetrahydroxydiborane, at 95% purity: China $5.96 for 5 g, $14.93 for 25 g, $49.30 for 100 g and $191.28 for 500 g, each from a single source. The US list prices were $23.91, $47.82, $100.43 and $478.24, 2.0 to 4.0 times the China index.

The China price per gram fell 68%, from $1.19 at 5 g to $0.38 at 500 g. With one source behind every China value, this is the least supported comparison in this report.

trans-2-Ethoxyvinylboronic acid pinacol ester

trans-2-Ethoxyvinylboronic acid pinacol ester (C10H19BO3, molecular weight 198.07) had the smallest US-to-China gap at the 100 g pack. At 98% purity the China index was $3.88 for 1 g (3 sources), $18.98 for 5 g (5 sources), $57.38 for 25 g (4 sources), $280.54 for 100 g (4 sources) and $608.37 for 500 g (2 sources). The US list prices were $23.91, $47.81, $119.54, $430.33 and $1,721.32, 1.5 to 6.2 times the China index; 1.53× at 100 g was the lowest ratio of any pack in this report.

The China price per gram did not fall steadily with pack size: $3.88 at 1 g, $3.80 at 5 g, $2.30 at 25 g, $2.81 at 100 g and $1.22 at 500 g.

Frequently asked questions

How much does phenylboronic acid cost?

In October 2026 the China price index for phenylboronic acid at 98% purity was $3.67 for 5 g, $17.78 for 100 g and $160.02 for 1 kg, from 4 to 9 sources. A US catalogue listed the same purity at $23.91 for 5 g, $119.53 for 100 g and $597.64 for 1 kg.

How much does potassium vinyltrifluoroborate cost?

At 97% purity the China index was $3.81 for 1 g, $21.67 for 25 g and $78.46 for 100 g, from 5 to 7 sources. A US catalogue listed $23.91, $71.74 and $227.16 for the same packs.

Which boron reagent is cheapest per mole?

Of the seven in this report, phenylboronic acid: $22 per mole in the China index at the 100 g pack and 98% purity, with methylboronic acid close behind at $24. In the US list prices, methylboronic acid was the cheapest per mole, at $72 against $146 for phenylboronic acid.

Is a larger pack always cheaper per gram?

Usually, but not always. In the China index, methylboronic acid cost $0.41 per gram at 500 g against $0.40 at 100 g, and trans-2-ethoxyvinylboronic acid pinacol ester $2.81 per gram at 100 g against $2.30 at 25 g.

Are these prices quotes I can buy at?

No. They are index values built from observed list prices. Actual prices depend on the supplier, the date, shipping, duties and order size.

Methodology

• Each product is identified by its CAS number and checked against its PubChem record.
• Listings are grouped by stated purity and pack size. Only the same purity and the same pack size are compared across regions; listings without a stated purity are left out.
• A listing counts for the US when its stock is located in the United States and for China when its stock is located in China.
• Each source is reduced to the median of its own listings; the regional index is the median across sources.
• Prices in Chinese yuan are converted at the latest European Central Bank reference rate before observation: 1 CNY = 0.14941 USD (12 October 2026) for phenylboronic acid and 4-fluorophenylboronic acid, 0.14942 USD (14 October 2026) for trans-2-ethoxyvinylboronic acid pinacol ester, and 0.14945 USD (15 October 2026) for the other four.
• Price per mole is the pack price divided by the pack mass in grams, multiplied by the molecular weight shown on the product page. It does not adjust for purity.
• The ratio in this report is the US value divided by the China value. Product pages show the same comparison as a percentage gap, (US − China) ÷ US.

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This report will be updated monthly. The product pages linked above always show the latest index.